. Author manuscript; available in PMC: 2018 Mar 1.

Published in final edited form as: Biol Blood Marrow Transplant. 2016 Dec 28;23(3):475–482. doi: 10.1016/j.bbmt.2016.12.623

Table 3. Cumulative incidence estimates of cardiovascular risk factors (CVRF) in childhood HCT survivors treated with TBI (n=123).

Outcome	N	Events	5-year cumulative incidence^* (95% CI)	10-year cumulative incidence^* (95% CI)
Elevated blood pressure	118	34	14.7 (8.6, 22.4)	28.8 (19.2, 39.2)
Elevated glucose	121	47	10.5 (5.5, 17.3)	33.1 (22.4, 44.1)
Low HDL-cholesterol	116	58	26.8 (18.8, 35.5)	52.0 (40.7, 62.2)
Hypertriglyceridemia	117	77	39.2 (29.8, 48.4)	65.0 (53.8, 74.2)
Obesity	123	21	16.0 (9.9, 23.4)	18.6 (11.7, 26.7)
CVRF cluster¹	123	35	10.6 (5.6, 17.5)	28.4 (18.8, 38.7)

HCT indicates hematopoietic cell transplantation; TBI, total body irradiation; CI, confidence interval; and HDL, high-density lipoprotein.

Cumulative incidence estimates reflect the time since TBI with time zero defined as one year after the date of TBI;

Defined as having 3 or more of the following CVRF: obesity, elevated blood pressure, elevated fasting glucose, low HDL, and elevated triglycerides.