Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Feb 20;10:1027–1038. doi: 10.2147/OTT.S125067

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2017 Zheng et al. This work is published and licensed by Dove Medical Press Limited

The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

PMC Copyright notice

miR-195 enhances radiosensitivity of CRC cells by regulating CARM1.

Notes: HCT-116 and HT-29 cells were transfected with miR-control or miR-195 mimics or co-transfected miR-195 mimics with pcDNA-control (pcDNA con) or pcDNA-CARM1. (A) The level of CARM1 was detected by Western blot. (B) Survival fractions were estimated in transfected HCT-116 and HT-29 cells after treatment with 0, 2, 4, 6, or 8 Gy of ionizing radiation. (C) Cell apoptosis assay of flow cytometry in transfected HCT-116 and HT-29 cells after treatment with ionizing radiation (4 Gy). Apoptosis-related proteins Bax, Bcl-2, and γ-H2AX were detected by Western blot in transfected HCT-116 (D) and HT-29 (E) cells after treatment with ionizing radiation (4 Gy). *P<0.05 vs control groups.

Abbreviations: NC, negative control; CRC, colorectal cancer.

miR-195 enhances radiosensitivity of CRC cells by regulating CARM1.

Notes: HCT-116 and HT-29 cells were transfected with miR-control or miR-195 mimics or co-transfected miR-195 mimics with pcDNA-control (pcDNA con) or pcDNA-CARM1. (A) The level of CARM1 was detected by Western blot. (B) Survival fractions were estimated in transfected HCT-116 and HT-29 cells after treatment with 0, 2, 4, 6, or 8 Gy of ionizing radiation. (C) Cell apoptosis assay of flow cytometry in transfected HCT-116 and HT-29 cells after treatment with ionizing radiation (4 Gy). Apoptosis-related proteins Bax, Bcl-2, and γ-H2AX were detected by Western blot in transfected HCT-116 (D) and HT-29 (E) cells after treatment with ionizing radiation (4 Gy). *P<0.05 vs control groups.

Abbreviations: NC, negative control; CRC, colorectal cancer.