Figure 6.

miR-195 upregulation increases CRC cell radiosensitivity in vivo.

Notes: HT-29 cells overexpressing miR-195 or miR-control were subcutaneously injected into nude mice aged 4–6 weeks. Radiation was performed with 8 Gy X-rays when the tumor volume was about 100 mm³. (A) Body weight of the mouse was determined every 5 days after radiation in different groups. (B) Image of representative tumor in different groups at Day 20 after radiation. (C) Weight of tumor in different groups at Day 20 after radiation. (D) Tumor growth curve in different groups. *P<0.05 vs control groups.

Abbreviation: CRC, colorectal cancer.