Table 3.

Comparison of hematological profiles between HAART-naïve and HAART-experienced HIV-infected children at Pediatric ART Clinic of Felege Hiwot Referral Hospital in Bahir Dar, northwest Ethiopia, 2013 (N=224)

Hematological values
Variables	HAART-naïve	HAART-experienced	Total	p-value
	Mean ± SD	Mean ± SD	Mean ± SD
Hg, g/dL	13.25±3.03	13.21±1.60	13.23±2.41	0.936
RBC, ×106/µL	4.48±0.58	4.94±4.75	4.71±3.39	0.319
HCT, %	38.21±4.85	38.43±4.00	38.32±4.44	0.708
MCV, fL	86.67±13.17	90.10±11.6	87.88±12.59	0.008**
MCH, pg	29.88±5.46	31.11±4.07	30.50±4.85	0.057
MCHC, g/dL	33.92±1.96	34.09±3.74	34.01±2.9	0.671
RDW, %	15.11±2.57	14.76±2.18	14.94±2.39	0.264
WBC, ×103/µL	8.18±3.32	8.01±3.26	8.09±3.29	0.708
ANC, ×103/µL	3.94±2.26	3.74±2.05	3.84±2.16	0.499
Lymphocyte count, ×103/µL	3.46±2.2	3.74±5.17	3.6±3.97	0.603
Mid (absolute), ×103/µL	1.34±1.7	2.21±8.10	1.76±5.77	0.247
Neutrophil, %	45.22±11.98	45.24±14	45.23±13.01	0.992
Lymphocyte, %	41.31±11.67	41.67±12.67	41.49±12.21	0.827
Mid, %	13.41±5.17	12.51±4.81	12.96±5	0.178
PLT, ×103cells/µL	297.91±107.67	300.99±105.10	299.45±06.16	0.829
MPV, %	9.72±1.92	9.82±7.96	9.77±5.77	0.899
CD4, cells/µL	873.16±466.53	767.86±486.60	820.51±78.52	0.100
CD4, %	28.73±14.22	24.78±10.69	26.73±12.71	0.018*

Note:

^*Significant at p<0.05;

^**significant at p<0.01 by independent t-test analysis.

Abbreviations: ANC, absolute neutrophil count; ART, antiretroviral treatment; CD4, cluster of differentiation-4; HAART, highly active antiretroviral therapy; HCT, hematocrit; HIV, human immunodeficiency virus; Hg, hemoglobin; MCH, mean corpuscular hemoglobin; MCHC, mean corpuscular hemoglobin concentration; MCV, mean corpuscular volume; mid, mixed cell; MPV, mean platelet volume; PLT, platelets; RBC, red blood cell; RDW, red cell distribution width; SD, standard deviation; WBC, white blood cell.