Table 6.
Factors associated with anemia among HAART-naïve and HAART-experienced children at Pediatric ART Clinic, Felege Hiwot Referral Hospital, northwest Ethiopia, April–May 2013 (N=224)
| Variable | Anemic status
|
Total (%) | COR (95% CI) | p-value | AOR (95% CI) | p-value | |
|---|---|---|---|---|---|---|---|
| Anemic (%) | Nonanemic (%) | ||||||
| Age, years | |||||||
| <5 | 24 (42.9) | 32 (57.1) | 56 (25) | 4.42 (1.83–10.68) | 0.001 | 4.3 (1.7–10.9) | 0.002 |
| 6–10 | 33 (31.1) | 73 (68.9) | 106 (47.3) | 2.66 (1.18–6.03) | 0.019 | 3.1 (1.3–7.2) | 0.011 |
| 11–14 | 9 (14.5) | 53 (85.5) | 62 (27.7) | 1 | – | 1 | – |
| Gastroenteritis | |||||||
| Yes | 7 (53.8) | 6 (46.2) | 13 (5.9) | 3.01 (0.97–9.32) | 0.057 | 2.9 (0.3–1.05) | 0.092 |
| No | 59 (28) | 152 (72) | 152 (94.1) | 1 | – | 1 | – |
| Bleeding | |||||||
| Yes | 3 (11.5) | 23 (88.5) | 26 (11.6) | 0.28 (0.08–0.97) | 0.044 | 0.3 (0.08–1.05) | 0.059 |
| No | 63 (31.8) | 135 (68.2) | 198 (88.4) | 1 | – | 1 | – |
| Immunological status | |||||||
| Severe immunosuppression | 19 (47.5) | 21 (52.5) | 40 (17.9) | 2.36 (1.08–5.2) | 0.032 | 2.95 (1.26–6.9) | 0.041 |
| Advanced immunosuppression | 5 (17.5) | 24 (82.8) | 29 (12.9) | 0.54 (0.0.2–1.6) | 0.27 | 0.67 (0.22–2.06) | 0.48 |
| Mild immunosuppression | 19 (26.4) | 53 (73.6) | 72 (32.1) | 0.94 (0.5–1.9) | 0.85 | 1.25 (0.59–2.66) | 0.55 |
| No immunosuppression | 23 (27.7) | 60 (72.3) | 83 (37.1) | 1 | – | 1 | – |
Abbreviations: AOR, adjusted odds ratio; CI, confidence interval; COR, crude odds ratio; HAART, highly active antiretroviral therapy.