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. 2017 Mar;61:340–352. doi: 10.1016/j.bbi.2016.12.013

Fig. 9.

Fig. 9

The effect of HDAC inhibitors on nuclear receptor-activated gene expression. The influence of inhibition of (A) HDAC4/5 by LMK235 or (B) HDAC6 by Tubastatin A on induction of Rarb by retinoic acid. The influence of inhibition of (C) HDAC4/5 by LMK235 or (D) HDAC6 by Tubastatin A on induction of Nrgn by thyroid hormone. qPCR quantification of gene expression is shown relative to Actb levels. ∗∗p < 0.01, ∗∗∗p < 0.001. Tub A, Tubastatin A; RA, retinoic acid; T3, thyroid hormone.