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. 2017 Feb 17;12:1353–1368. doi: 10.2147/IJN.S126865

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© 2017 Chu et al. This work is published and licensed by Dove Medical Press Limited

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Fluorescence microscopy images of the cellular uptake of NPs with 5, 20, and 40% TAT–PEG–PLGA in HUVECs.

Notes: iRGD–5% TAT-Nile red-NP, iRGD and TAT dual-modified NPs labeled with Nile red with 5% TAT–PEG–PLGA; iRGD–20% TAT-Nile red-NP, iRGD and TAT dual-modified NPs labeled with Nile red with 20% TAT–PEG–PLGA; iRGD–40% TAT-Nile red-NP, iRGD and TAT dual-modified NPs labeled with Nile red with 40% TAT–PEG–PLGA.

Abbreviations: HUVECs, human umbilical vein endothelial cells; iRGD, internalizing arginine-glycine-aspartic acid; NP, nanoparticle; PEG, poly(ethylene glycol); PLGA, poly(lactic-co-glycolic acid); TAT, transactivated transcription.