Table 1.

Formulation of various nanoparticles

Groups	mPEG–PLGA (mg)	iRGD–PEG–PLGA (mg)	TAT–PEG–PLGA (mg)	Nile red (mg)	Acetone (mL)	Deionized water (mL)
mPEG–PLGA-Nile red-NP	40	–	–	0.4	4	40
iRGD-Nile red-NP	30	10	–	0.4	4	40
TAT-Nile red-NP	30	–	10	0.4	4	40
iRGD–TAT-Nile red-NP	20	10	10	0.4	4	40

Notes: iRGD–PEG–PLGA, iRGD-modified PEG–PLGA; TAT–PEG–PLGA, TAT-modified PEG–PLGA; mPEG–PLGA-Nile red-NP, mPEG–PLGA NPs labeled with Nile red; iRGD-Nile red-NP, iRGD-modified NPs labeled with Nile red; TAT-Nile red-NP, TAT-modified NPs labeled with Nile red; iRGD–TAT-Nile red-NP, iRGD and TAT dual-modified NPs labeled with Nile red.

Abbreviations: iRGD, internalizing RGD; mPEG, methoxy-poly(ethylene glycol); NP, nanoparticle; PEG, poly(ethylene glycol); PLGA, poly(lactic-co-glycolic acid); TAT, transactivated transcription.