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. 2017 Feb 24;12(2):e0171193. doi: 10.1371/journal.pone.0171193

Fig 3. Altered IL-6 and IP-10 levels in SLE patients and lupus relatives.

Fig 3

Plasma levels of IL-6 (A, C) and IP-10 (B, D) were assessed in SLE patients (case), unaffected first-degree relatives of SLE patients (FDR), and unrelated, unaffected controls with no family history of SLE (Ctl). IL-6 (C) and IP-10 (D) levels are compared by genotype of associated SNPs rs76162067 and rs79711023, respectively. Data are presented as mean + SEM. *p<0.05, **p<0.01, ***p<0.001, ****p<0.0001 by Kruskal-Wallis test with Dunn’s multiple comparison for all groups assessed (Case/FDR/Ctl [A-B]; Case/FDR/Ctl carrying major (CC) or minor (TC) alleles [C-D]). Only comparisons found to be statistically significant were marked.