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. 2017 Feb 24;12(2):e0172795. doi: 10.1371/journal.pone.0172795

Fig 2. Proliferation and cytokines production of naïve OVA-specific CD4+ T cells from R23-3 and RD10 mice.

Fig 2

Naïve OVA-specific CD4+ T cells purified from R23-3 (●) and RD10 (○) mice (n = 3 each) were stimulated with both anti-CD3 mAb and anti-CD28 mAb. A, Proliferation of OVA-specific CD4+ T cells. B, IL-4 (upper panel) and IFN-γ (lower panel) production in culture supernatants of OVA-specific CD4+ T cells. These results are representative of two independent experiments; *, P< 0.05; **, P < 0.01.