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. 2017 Feb 24;12(2):e0172627. doi: 10.1371/journal.pone.0172627

Fig 3. Histopathology observed in mice with rear leg clinical signs assocaited with IP challenge with B. pseudomallei K96243.

Fig 3

(A) C57BL/6 euthanized on day 22 post-infection showing clinical signs in the hind-end and tail. Tail, transverse section: Multiple pyogranulomas partially effacing vertebral body and associated soft tissues. H&E, 20X. (B) BALB/c mouse euthanized on day 25 post-infection with rear-leg paralysis and labored breathing. Lumbar spine, longitudinal section: Pyogranulomatous inflammation partially effacing vertebral body and associated soft tissues. P = pyogranuloma; M = marrow cavity; V = vertebral body; H&E, 40X.