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. 2017 Feb 24;12(2):e0172627. doi: 10.1371/journal.pone.0172627

Fig 13. Changes in the amount of cytokines/chemokines in sera from BALB/c and C57BL/6 mice after aerosol exposure to B. pseudomallei K96243.

Fig 13

The amount of cytokines/chemokines present in sera (S7 Table) was determined. For changes in cytokine/chemokine levels in sera from BALB/c mice (A), we show changes in levels up to 22 days post exposure because there were no survivors after that period. We also show changes in cytokine/chemokine levels in sera for C57BL/6 mice (B) up to 22 days for comparison and not many significant changes occurred after 22 days in sera from C57BL/6 mice. For each mouse strain N = 5 at each time point. Fold-changes in cytokines/chemokines were determined by dividing the amount (pg/ml) present in sera of exposed mice (S7 Table) by the mount present in normal, naïve mice, where N = 10 for BALB/c and N = 4 for C57BL/6 mice. For C57BL/6 mice fold-change for MIG was not shown because it was very high (235-fold), and it would make obscure the changes in the levels of the other cytokines/chemokines at the same time.