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. 2016 Aug 30;7(39):62814–62835. doi: 10.18632/oncotarget.11716

Table 3B. Quantification of PAX3-FOXO1-dependent chromosomal structural abnormalities.

Sample Number cells analyzed Sister Chromatid Dissociation Telomere Association Double Minutes
Number of Cells Range of Events/Cell Number of Cells Range of Events/Cell Number of Cells Range of Events/Cell
Vector 62 1 (1.6%) 2 2 (3.2%) 2 0 (0.0%) 0
PAX3 50 2 (4.0%) 2 2 (4.0%) 2 0 (0.0%) 0
PAX3-FOXO1 103 16 (15.5%) 1 – 5 17 (16.5%) 1 – 16 4 (3.9%) 5 – 20
S201A 64 6 (9.4%) 2 – 6 21 (32.8%) 2 – 18 4 (6.3%) 6 – 12
S205A 69 9 (13.0%) 1 – 3 20 (28.9%) 1 – 4 5 (7.2%) 1 – 62
S209A 57 7 (12.3%) 5 – 63 6 (10.5%) 1 – 3 4 (7.0%) 5 – 40

Metaphase chromosome analysis on cells stably transduced with empty vector (Vector), PAX3, PAX3-FOXO1, or the PAX3-FOXO1 phosphomutants (S201A, S205A, or S209A). The number of cells containing the indicated structural abnormality along with a range of the number of occurrences of the abnormality within each cell is listed.