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. 2016 Aug 12;7(39):63138–63157. doi: 10.18632/oncotarget.11257

Figure 6. STn overexpression co-localizes with high nuclear HIF-1α expression areas.

Figure 6

HIF-1α presents mainly a cytoplasmic expression and strong diffused expression troughout the cell when nuclear staining is present. (A) Advanced stage bladder tumour showing low levels of nuclear HIF-1α (low hypoxic tumour; 200× magnification). (B) Advanced stage bladder tumour showing high levels of nuclear HIF-1α (high hypoxic tumour; 200× magnification). (C) Advanced stage bladder tumour area showing high STn expression (100× magnification). (D) STn-positive advanced stage bladder tumour area with high nuclear HIF-1α expression (100× magnification).