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. 2016 Aug 12;7(39):63138–63157. doi: 10.18632/oncotarget.11257

Table 1. Nuclear HIF-1α phenotype in bladder tumours in different stages of the disease.

Tumour Stage Tumour hypoxia based on nuclear HIF-1α χ2
Low High Low High
Ta (15) 11 (73%) 4 (27%) NMIBC NMIBC p < 0.05
T1 (15) 6 (40%) 9 (60%) 17 (57%) 13 (43%)
T2 (13) 4 (31%) 9 (69%)
T3 (15) 5 (33%) 10 (67%) MIBC MIB C
T4 (15) 3 (20%) 12 (80%) 12 (28%) 31 (72%)
Total (73) 29 (40%) 44 (60%)