Table 2. Main information of various diagnostic models for PHC.
| Model | Variables in model# | Nagelkerke Pseudo R2 | Likelihood ratio test | |
|---|---|---|---|---|
| χ2 | P | |||
| F-M | FTDS15E, FS15T8, FS3T8E, FS3T8, FS3T37, FS3T37E, FS15T37, FTDS3, FTDS15, FEDS3T37 | 0.711 | 1062.7 | 0.000 |
| A-M | AFP | 0.321 | 356.2 | 0.000 |
| H-M | TBIL, ALT, AST, DBIL, ALB | 0.814 | 1409.4 | 0.000 |
| B-M | PLT, WBC, Hb | 0.552 | 700.6 | 0.000 |
| FA-M | AFP, FS15T37E, FS15T37, FS3T37E, FS3T8, FS3T8E, FS15T8, FS15T8E | 0.737 | 1169.3 | 0.000 |
| FH-M | TBIL, ALT, FS15T37E, FS3T37E, FS3T8, FS15T8, FS15T8E, AST, DBIL, ALB | 0.877 | 1719.2 | 0.000 |
| FB-M | PLT, RBC, FS15T8E, FS15T8, FS3T8E, FS3T8, FS3T37E, FS15T37, WBC, Hb | 0.795 | 1362.6 | 0.000 |
| FAHB-M | PLT, ALT, FS15T8E, FS15T8, FS3T8, FS3T37E, FS15T37, AFP, AST, ALB, WBC, Hb | 0.909 | 1857.4 | 0.000 |
Note: #The variables in the models were transformed with a natural logarithm. Each model name is a combination of abbreviations representing the fluorescence intensity (F), alpha-fetoprotein (A), hepatic function tests (H) and/or blood cell analyses (B) with the model (−M), indicating the covariates used during modeling; for example, FAHB-M was established with the indicators of fluorescence intensity, alpha-fetoprotein, hepatic function tests and blood cell analyses. The fluorescence indicators represent the fluorescence intensity (F) of 3 μL (S3) or 15 μL (S15) serum samples at a detection temperature of 8°C (T8) or 37°C (T37) in the presence (E) or absence of EvaGreen. AFP: alpha-fetoprotein, ALT: alanine transaminase; AST: aspartate transaminase; TBIL: total serum bilirubin; DBIL: direct serum bilirubin; ALB: serum albumin; WBC: white blood cell; RBC: red blood cell; Hb: hemoglobin; PLT: platelet.