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. 2016 Sep 1;7(39):64309–64317. doi: 10.18632/oncotarget.11790

Figure 2. High expression of LCN2 promoted CRPC cell proliferation.

Figure 2

A. Expression of LCN2 was dramatically increased in C4-2B and 22RV1 cells infected with a lentivirus encoding the LCN2 gene. B. Expression of LCN2 was decreased in C4-2B and 22RV1 cells afected with the LCN2 siRNA. C. A cell proliferation assay revealed that overexpression of LCN2 significantly enhanced the growth rate of C4-2B and 22RV1 cells. The knockdown of LCN2 markedly inhibited cell growth in C4-2B and 22RV1 cells. D. A colony formation assay confirmed that LCN2 overexpression promotes the proliferation of C4-2B and 22RV1 cells.