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. 2016 Jul 28;7(39):64421–64430. doi: 10.18632/oncotarget.10910

Table 3. Multivariate Cox regression model.

Cox Model HR 95% CI P
Ewings vs. Osteosarcoma 1.2 0.6, 2.7 0.56
Chondrosarcoma vs. Osteosarcoma 0.8 0.3, 2.2 0.7
Other tumor type vs. Osteosarcoma 0.1 0.3, 0.6 0.0084
Sex: male vs. female 2.2 1.1, 4.4 0.025
Body surface area: ≥2 vs. <2 1.7 0.8, 3.4 0.16
Number of metastatic sites: >2 vs. ≤2 2.6 1.4, 4.8 0.0023
Number of prior therapies: >3 vs. ≤3 1.9 1.0, 3.5 0.042
Hemoglobin: <10.5 vs. ≥10.5 g/dL 4.4 2.1, 9.2 <0.0001
Platelets: <200 vs.>200 × 103/L 2.1 1.2, 3.9 0.015
Lactate dehyrdogenas (LDH): ≤618 [normal] vs. >618 U/L [>ULN] 2.2 1.1, 4.2 0.018
Creatinine: <1.3 vs. ≥1.3 mg/dL 0.4 0.1, 0.9 0.024

Note: Age, ECOG PS, Bilirubin, and Albumin were removed from the model due to p > 0.50. Adding Prior Radiation to the above model gives HR = 0.5 (0.3, 1.0) with p = 0.070.