Table 1. Molecular subtype, p53 mutational status and other key mutations of breast cancer cell lines used in this study.

Cell Line Name	Molecular Subtype	p53 Status	Mutations
MDA-MB-231	TNBC / Claudin Low	mt R280K	KRAS, BRAF, CDKN2A
BT-549	TNBC / Claudin Low	mt R249S	PTEN, RB1
SUM-159	TNBC / Claudin Low	mt R158InF	HRAS, PIK3CA
T-47D	ER+ / Luminal A	mt L194F	PIK3CA
MCF-7	ER+ / Luminal A	WT	PIK3CA, CDK2NA
MCF-10A	Non-cancerous	WT