Table 1. Molecular subtype, p53 mutational status and other key mutations of breast cancer cell lines used in this study.
Cell Line Name | Molecular Subtype | p53 Status | Mutations |
---|---|---|---|
MDA-MB-231 | TNBC / Claudin Low | mt R280K | KRAS, BRAF, CDKN2A |
BT-549 | TNBC / Claudin Low | mt R249S | PTEN, RB1 |
SUM-159 | TNBC / Claudin Low | mt R158InF | HRAS, PIK3CA |
T-47D | ER+ / Luminal A | mt L194F | PIK3CA |
MCF-7 | ER+ / Luminal A | WT | PIK3CA, CDK2NA |
MCF-10A | Non-cancerous | WT |