Table 2. Total incidence rate change 1975–2012 and estimated change in diagnoses nationally.

Diagnostic GROUP/Sitea	Male						Female						Total
	Change in ratesb	Change in number of diagnoses	1975 Rate	Estimated 2012 diagnoses using 1975 rate	2012 Rate	Estimated 2012 diagnoses	Change in rates	Change in number of diagnoses	1975 Rate	Estimated 2012 diagnoses using 1975 rate	2012 Rate	Estimated 2012 diagnoses	Change in rates	Change in number of diagnoses	1975 Rate	Estimated 2012 diagnoses using 1975 rate	2012 Rate	Estimated 2012 diagnoses
TOTAL	5.18	568	18.62	2,040	23.80	2,608	4.62	480	17.77	1,847	22.39	2,328	4.91	1,050	18.20	3,887	23.12	4,936
LEUKEMIAS	0.35	38	2.67	292	3.02	331	0.94	98	1.54	160	2.48	258	0.65	138	2.11	451	2.76	589
Acute lymphoid leukemia	0.44	48	1.44	158	1.88	206	0.44	46	0.64	66	1.08	112	0.87	185	0.97	208	1.84	393
Acute myeloid leukemia	0.19	21	0.74	81	0.93	102	0.47	49	0.58	60	1.05	109	0.37	80	0.64	136	1.01	216
LYMPHOMAS	0.26	28	5.21	571	5.46	599	-0.08	-8	4.90	510	4.82	501	0.10	20	5.06	1080	5.15	1,100
Non-Hodgkin lymphoma	0.93	102	1.55	170	2.48	272	0.72	75	0.83	86	1.55	161	0.68	145	1.21	259	1.89	404
Hodgkin lymphoma	-0.68	-75	3.66	401	2.98	327	-0.81	-84	4.08	424	3.27	340	-0.98	-209	3.89	831	2.91	622
CNS, INTRACRANIAL, INTRASPINAL	0.21	23	2.14	235	2.35	258	0.31	32	1.57	163	1.88	195	0.26	56	1.86	397	2.12	453
Astrocytoma	-0.20	-22	1.40	153	1.19	131	0.06	6	1.01	105	1.07	112	-0.07	-15	1.21	258	1.14	243
OSSEOUS & CHONDROMATOUS NEOPLASMS	0.6	66	1.75	192	2.35	258	0.01	1	1.11	115	1.12	117	0.32	68	1.43	306	1.75	375
Osteosarcoma	0.25	27	0.94	104	1.20	131	-0.09	-9	0.63	65	0.53	55	0.09	19	0.79	170	0.88	188
SOFT TISSUE SARCOMAS	0.23	25	1.43	157	1.66	182	0.11	11	1.39	144	1.50	156	0.17	37	1.41	301	1.58	338
GERM CELL AND TROPHOBLASTIC NEOPLASMS	1.59	174	2.77	304	4.37	479	-0.14	-15	1.43	149	1.29	134	0.76	163	2.11	451	2.87	613
Testicular/Ovarian	1.6	175	2.17	238	3.77	413	0.1	10	1.04	108	1.14	118	0.89	189	1.61	344	2.50	533
MELANOMA AND SKIN CARCINOMAS	0.45	49	0.96	105	1.41	154	0.5	52	1.63	170	2.13	222	0.47	101	1.29	275	1.76	376
Melanoma	0.43	47	0.95	104	1.38	151	0.52	54	1.61	168	2.13	222	0.11	23	1.36	289	1.46	312
CARCINOMAS (excluding skin)	1.05	115	1.44	158	2.49	273	2.62	272	3.83	398	6.45	671	1.79	383	2.62	560	4.41	943
Thyroid	0.39	43	0.40	44	0.79	87	2.57	267	1.79	186	4.36	453	1.12	239	1.16	247	2.27	486
MISCELLANEOUS SPECIFIED NEOPLASMS, NOS	0.44	48	0.17	19	0.62	68	0.31	32	0.29	30	0.60	62	0.35	74	0.25	54	0.60	128

^aClassification scheme for tumors diagnosed in adolescents and young adults (Barr 2006).

^bChange in predicted rates calculated from SEER 9 registries, 1975–2012.