Fig 1. Assessment of YHJ-7-52 biological activities in hMSC culture models.

(A) Human MSCs were incubated for 24 h with YHJ-7-52 and YHJ-7-82 at various concentrations (0–100 μM) and then counted. Human MSC were induced towards an adipogenic lineage in the presence of either 10 μM YHJ-7-52, 10 μM YHJ-7-82, or DMSO control. (B) Relative lipid accumulation as determined by imageJ. YHJ-7-52 reduced lipid accumulation by 36%. (C) Representative images of each condition. Results are displayed as mean ± standard error. Scale bar 150 μm. ** P < 0.05