Table 1. Frequency, severity and duration of the severest episode of any adverse drug-related reaction (ADR), treatment completion rates and medication adherence in 76 patients treated with benznidazole in Pampa del Indio, excluding two patients with an early dropout.
Nd, no data.
| Type of ADR | Severity | No. of patients (%) | Mean duration of severest# episode (days) | Medication adherence (%)## | Treatment completion |
|---|---|---|---|---|---|
| None | None | 52 (69) | 0 | 97 | 48 (92) |
| Exanthema | Mild | 10 (13)* | 2.1 | 96 | 9 (90) |
| Moderate | 5 (7)** | 5.6 | 100 | 4 (80) | |
| Severe | 3 (4)*** | 2.7 | 100 | 0 (0) | |
| Unknown | 3 (4) | 4.0 | 82 | 2 (67) | |
| Dizziness | Mild | 1 (1) | Nd | 100 | 1 (100) |
| Headache | Moderate | 1 (1) | Nd | 100 | 1 (100) |
| Gastrointestinal | Mild | 1 (1) | Nd | 94 | 1 (100) |
| Total | 76 | 3.4 | 97 | 66 (87) |
* One combined with mild myalgia and severe arthralgia.
** One combined with mild headache.
*** One combined with mild fever.
# Computed among participants displaying ≥1ADR episode.
## Computed among participants who completed the full treatment course.