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. 2017 Feb 24;12(2):e0173076. doi: 10.1371/journal.pone.0173076

Table 1. Offspring biometric data, energy metabolism and plasma parameters.

    No exercise (-RW) Exercise (+RW) p-Value
  Con mLFD mHFD mLFD mHFD mDiet RW
Biometric data
Lean mass at wk 7 [g] 20.35 ± 0.75 21.74 ± 0.81 21.57 ± 0.41 20.76 ± 0.79 22.05 ± 0.52 n.s. n.s.
Fat mass at wk 7 [g] 1.20 ± 0.10 1.10 ± 0.08 1.35 ± 0.09 1.41 ± 0.11 1.27 ± 0.08 n.s. n.s.
Lean mass at wk 15 [g] 23.30 ± 0.59 24.66 ± 0.62 24.40 ± 0.45 23.87 ± 0.75 24.57 ± 0.46 n.s. n.s.
Fat mass at wk 15 [g] 2.62 ± 0.35 2.68 ± 0.44 3.23 ± 0.49 1.42 ± 0.17 2.46 ± 0.33 0.057 <0.05
Lean mass at wk 25 [g] 24.37 ± 0.54 26.30 ± 0.75 26.44 ± 0.65 25.40 ± 0.83 26.43 ± 0.64 n.s. n.s.
Fat mass at wk 25 [g] 2.98 ± 0.45 6.80 ± 1.14 9.67 ± 1.22 5.26 ± 0.82 7.65 ± 1.24 <0.05 n.s.
Energy metabolism
EE [kJ/d] 55.5 ± 0.9 56.8 ± 1.7 57.8 ± 2.0 55.6 ± 2.3 56.4 ± 1.6 n.s. n.s.
RQ 0.95 ± 0.01 0.84 ± 0.01 0.83 ± 0.01 0.86 ± 0.01 0.86 ± 0.01 n.s. n.s.
Plasma parameters
TG [mmol/L] 0.421 ± 0.054 0.402 ± 0.094 0.286 ± 0.063 0.460 ± 0.086 0.411 ± 0.082 n.s. n.s.
NEFA [mmol/L] 0.662 ± 0.035 0.568 ± 0.084 0.669 ± 0.072 0.616 ± 0.065 0.562 ± 0.053 n.s. n.s.
Chol [mg/dL] 200.4 ± 16.8 212.6 ± 21.5 227.1 ± 20.6 217.4 ± 31.5 200.2 ± 21.6 n.s. n.s.

Maternal low-fat diet (mLFD) or maternal high-fat diet (mHFD) offspring were fed a LFD after weaning throughout an age of 15 wks. Afterwards they received HFD for 10 wks. Half of each group had access to a running wheel (RW) for voluntary training. As control group (Con) mLFD offspring -RW were fed a LFD. Data are mean ±SE, n = 6-12. Indirect calorimetry for determination of energy expenditure and RQ was performed in wk 24, plasma data are from wk 25 after sacrifice. Data were compared by two-way ANOVA (Bonferroni post hoc test).