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. 2017 Mar;67(656):134–135. doi: 10.3399/bjgp17X689809

Table 1.

Diseases caused by vitamin B deficiencies

Vitamin Disease Effect
Vitamin B1 (thiamine) Wernicke–Korsakoff syndrome (WKS) Acute and chronic brain syndrome
Beri-beri Cardiomyopathy, with or without cardiac failure
Vitamin B2 (riboflavin) Dementia Chronic brain syndrome
Anaemia
Dermatitis and glossitis
Vitamin B3 (nicotinic acid/niacin) Pellagra Irritable skin rashes, glossitis
Encephalopathy Lower seizure threshold, disturbed higher mental executive functions and memory
Enteropathy Diarrhoea
Vitamin B6 (pyridoxine) Peripheral neuropathy Sensory, often painful
Cardiomyopathy Reduced heart function, heart failure
Dermatitis Irritable skin rashes
Folic acid Anaemia
Neural tube defects in foetus
Neuropathy and encephalopathy Including peripheral neuropathy, subacute degeneration of spinal cord, cerebral atrophy
Macular degeneration Reduced central vision
Vitamin B12 Anaemia
Neuropathy and encephalopathy Peripheral neuropathy, subacute combined degeneration of the spinal cord, cognitive impairment
Psychiatric syndromes Anxiety and irritability
Depression
Psychosis
Cardiomyopathy Reduced heart function, heart failure