Table 2. Comparison of Hormone Concentrations in Response to AG and DAG.

Differences of Least Squares Means (LSM) comparison of plasma norepinephrine (NE) and epinephrine between AG (1 μg/kg/h), DAG (4 μg/kg/h), and saline infusions in 10 healthy men and women. Differences of LSM comparison of renin and aldosterone levels with AG, combined AG + DAG, and saline infusion are also presented. No significant differences in NE, epinephrine, renin, and aldosterone were observed between saline control and peptide infusion treatments. AG and combined AG + DAG treatment significantly increased plasma aldosterone levels compared to control (p<0.0001 for AG vs Saline; p=0.0002 for AG vs Combined).

	Treatment	Comparison	Δ LSM	SE	DF	T-Value	Pr > |t|
Aldosterone	AG	Saline	30.242	5.60	16	5.40	<.0001
		DAG	25.440	5.20	16	4.89	0.0002
	DAG	Saline	4.802	5.59	16	0.86	0.4028
Renin	AG	Saline	2.165	2.39	16	0.91	0.3783
		DAG	3.960	2.20	16	1.80	0.0910
	DAG	Saline	−1.795	2.39	16	−0.75	0.4642
NE	AG	Saline	32.543	81.58	18	0.40	0.6946
		DAG	95.668	110.69	18	0.86	0.3988
	DAG	Saline	63.123	81.30	18	0.78	0.4476
Epi	AG	Saline	18.576	16.67	18	1.11	0.2799
		DAG	26.571	16.52	18	1.61	0.1252
	DAG	Saline	7.995	16.60	18	0.48	0.6360

^*AG = acyl ghrelin, DAG = desacyl ghrelin, Com = Combined AG + DAG, NE = norepinephrine, Epi = epinephrine, DF = Degrees of freedom, ΔLSM = differences of Least Squares Means; SE = Standard Error