TABLE II.
Penetrance Calculations
Phenotype | Number assessed for each phenotype | Number with phenotype (who define critical region) | Number hemizygous for the critical region without phenotype | Number hemizygous for critical region (both with and without the phenotype) | % Non-penetrance | % Penetrance |
---|---|---|---|---|---|---|
Kidney malformation | 72 | 13 | 39 | 52 | 39/52 = 75 | 25 |
Dysmyelination | 88 | 80 | 0 | 80 | 0/80 = 0 | 100 |
Growth hormone response failure | 99 | 46 | 9 | 89 | 9/89 = 10 | 90 |
Aural atresia | 116 | 81 | 23 | 104 | 23/104 = 22 | 78 |