Table 1.
Alopecia and control patient demographic and clinical characteristics
| Variables | Female androgenetic alopecia (n=115) | Controls (n=97) | p value* |
|---|---|---|---|
| No. patients (%) | 115 (21.1) | 97 (78.9) | |
| Age (years) (mean ± SD) | 36.28 ± 8.92 | 36.07 ± 9.00 | 0.868 |
| Occupation (%) | 0.591 | ||
| Housewife | 66 (57.4) | 57 (58.8) | |
| Officer | 20 (17.4) | 22 (22.7) | |
| Worker | 13 (11.3) | 6 (6.2) | |
| Student | 4 (3.5) | 2 (2.1) | |
| Retired/unemployed | 12 (10.4) | 10 (9.7) | |
| Marital status (%) | 0.049** | ||
| Married | 98 (85.2) | 76 (78.4) | |
| Single | 15 (10.4) | 12 (12.4) | |
| Divorced/separated | 2 (1.7) | 9 (9.3) | |
| Family history (%) | 46 (40.0) | 10 (10.3) | <0.001 |
| Cardiovascular event (%) | 10 (8.7%) | 8 (8.2) | 0.907 |
| Height (cm) (mean ± SD) | 161.70 ± 6.02 | 161,87 ± 5.54 | 0.986 |
| Weight (kg) (mean ± SD) | 70.46 ± 15.85 | 65.25 ± 10.06 | 0.030 |
| Waist circumference (mean ± SD) | 90.42 ± 13.46 | 82.73 ± 10.81 | <0.001 |
| Hip circumference (mean ± SD) | 106.99 ± 10.10 | 100.25 ± 10.79 | <0.001 |
| Neck circumference (mean ± SD) | 33.54 ± 3.89 | 33.94 ± 2.78 | 0.416 |
| Waist to hip ratio (mean ± SD) | 0.84 ± 0.07 | 0.82 ± 0.06 | 0.034 |
| Body mass index (mean ± SD) | 26.94 ± 5.81 | 24.92 ± 3.80 | 0.009 |
| High FPG (%) | 17 (14.8) | 7 (7.2) | 0.083 |
| Hypertension (%) | 32 (27.8) | 16 (16.5) | 0.050 |
| Large waist (%) | 67 (58.3) | 34 (35.1) | 0.001 |
| High TG (%) | 20 (17.4) | 7 (7.2) | 0.027 |
| Low HDL (%) | 64 (55.7) | 63 (64.9) | 0.169 |
| Metabolic syndrome (%) | 28 (24.3) | 14 (14.4) | 0.071 |
| Total testosterone (mean ± SD) | 0.38 ± 0.19 | 0.36 ± 0.19 | 0.461 |
| Free testosterone (mean ± SD) | 1.70 ± 0.83 | 0.32 ± 0.12 | 0.041 |
| FSFI score (mean ± SD) | 25.43 ± 6.88 | 27.55 ± 5.58 | 0.047 |
| Female sexual dysfunction (%) | 60 (52.2) | 35 (36.1) | 0.019 |
| Desire disorder (%) | 62 (53.9) | 26 (26.8) | <0.001 |
| Arousal disorder (%) | 35 (30.4) | 17 (17.5) | 0.030 |
| Lubrication disorder (%) | 47 (40.9) | 32 (32.9) | 0.237 |
| Orgasmic disorder (%) | 48 (41.7) | 32 (32.9) | 0.237 |
| Satisfaction disorder (%) | 42 (36.5) | 26 (26.8) | 0.131 |
| Sexual pain disorder (%) | 40 (34.8) | 41 (42.3) | 0.264 |
*
statistically significant at p<0.05;
**
Mann-Whitney U test was performed to test the significance of pairwise differences for using Bonferroni correction to adjust for multiple comparisons; FPG: fasting plasma glucose HDL: high-density lipoprotein; SD: standard deviation; TG: trigyceride.