Table 4.

Hazard ratios and 95% confidence intervals for incident events and all-cause mortality with log(TAC+1).

	Model 1		Model 2		Model 3
	HR (95% CI)	p	HR (95% CI)	p	HR (95% CI)	p
CHD All	1.00 (0.87 – 1.16)	0.954	0.97 (0.83 – 1.13)	0.681	0.93 (0.79 – 1.08)	0.339
CHD Hard	1.01 (0.85 – 1.18)	0.944	0.98 (0.82 – 1.16)	0.796	0.94 (0.78 – 1.12)	0.459
CVD All	1.15 (1.06 – 1.24)	0.001	1.08 (0.99 – 1.18)	0.070	1.03 (0.94 – 1.13)	0.529
CVD Hard	1.14 (1.04 – 1.25)	0.004	1.09 (0.98 – 1.20)	0.098	1.04 (0.94 – 1.15)	0.425
Stroke	1.22 (1.09 – 1.36)	<0.001	1.13 (1.00 – 1.28)	0.045	1.09 (0.96 – 1.24)	0.183
TIA	1.23 (1.04 – 1.45)	0.014	1.23 (1.02 – 1.49)	0.030	1.18 (0.97 – 1.45)	0.100
All-cause mortality	1.23 (1.16 – 1.30)	<0.001	1.09 (1.02 – 1.16)	0.008	1.06 (0.99 – 1.13)	0.101

Data presented as hazard ratios and 95% confidence intervals.

Model 1: Unadjusted.

Model 2: Adjusted for age, sex and race/ethnicity.

Model 3: Adjusted for Model 2 + smoking status, diabetes, systolic blood pressure, hypertension medication use, total cholesterol, HDL cholesterol, lipid-lowering medication use, EGFR, and family history of heart disease at any age.

CHD, coronary heart disease; CI, confidence interval; CVD, cardiovascular disease; HR, hazard ratio; TIA, transient ischemic attack.