Effects of estrogen on wave reflection in PAH. (A) Pulse wave velocity (PWV), (B) Global wave reflection index, (C) difference in systolic pressure between measured and forward pressure waves, (D) difference in pulse pressure between measured and forward pressure waves, and (E) normalized time between the beginning of systolic pressure wave to the peak of the reflected pressure wave (tpeak = Δt/T). *, P<0.05 vs. Control, #, P<0.05 vs. Placebo.