Figure 4.

S1PR1 blockade reduces KLRG1− CD4 T cells in the lung vasculature.\r\n (A) Representative FACS plots of Lung I-A^b:ESAT-6_4-17 tetramer+ CD4 T cells from H56/CAF01-vaccinated (lower plots) and adjuvant control (upper plots) C57BL/6 mice infected for 7 weeks with Mtb followed by 48hr treatment with (right) or without (left) FTY720. (B) Bar graph shows the proportion of KLRG1− of I-A^b:ESAT-6_4-17 tetramer+ CD4 T cells in the lung vasculature (IV+) for each treatment group. Bar, mean+/−SEM of n=3 mice per group. *p<0.05.\r\n