Fig. 2.

Interferon score plotted for each sample according to genotype/phenotype. a 455 group 1 patient samples. b 30 group 2 patient samples. c 340 group 3 patient samples. Black horizontal lines represent the median for each patient group. Interferon scores calculated from the median fold change in RQ (relative quantification) values of a panel of six interferon-stimulated genes (ISGs). Blue dots represent an interferon score of less than 2.466. Red dots represent an interferon score of greater than 2.466. Magenta dots represent patients treated with IL1 blockade. Analyzed by one-way ANOVA with Dunnett’s multiple comparison test