Fig. 4.

Interferon scores in patients where four or more serial samples were recorded. Data shown are interferon scores plotted against time (years) since first sampling. Interferon scores are calculated from the median fold change in relative quantification (RQ) values for a panel of six interferon-stimulated genes (ISGs). The blue dashed line represents the boundary of a positive/negative score (2.466). The number of serial samples for each patient is shown in brackets in the legend