Fig. 6.

Output of naïve T cells by sjTREC content. The single joint T cell receptor excision circle (sjTREC) content was measured as a marker for thymic output of naïve T cells. The y-axis represents the ΔCt (difference in amplification cycles between TREC and albumin as a control for DNA input). The TREC content was determined of six NBS patients (black dots) and compared to eight age-matched HI (open dots). Data represents individual measurements and medians. Significant differences between patients and HI and between different age groups were calculated and shown (** = p < 0.01)