Figure 4.

Genomic imprinting and associated pathologies. Predicted patterns of parent-of-origin-specific gene expression and concomitant phenotypes for loci that are either promoters or inhibitors of belligerence (a) or bravery (b), under normal conditions and also as a result of three different mutational or epimutational perturbations: gene deletion, imprinting disruption, or uniparental disomy. Genes are either of maternal-origin (orange) or paternal-origin (blue) and are either silenced (crosses) or expressed (arrows). Human figures from the George Stow collection at Iziko South African Museum, derived from The Digital Bleek and Lloyd (http://lloydbleekcollection.cs.uct.ac.za/) with permission. (Online version in colour.)