Figure 1.
AprA and DPPIV have similar structures. (A,B) The predicted structure of AprA, shown in cyan, is superimposed with the α/β hydrolase domain of DPPIV (Protein Data Bank ID 1J2E), shown in green. The catalytic triad of DPPIV (Asp708, His740, and Ser630) is orange while the predicted catalytic triad of AprA (Asp288, His319, and Ser195) is blue. The predicted structure of AprA did not overlap with the β‐propeller domain of DPPIV. Therefore, the β‐propeller domain was removed for simplicity of the image.