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Antiviral efficacy and cytotoxicity of compounds 3, 7, and 16.
| Compounds | Antiviral Efficacy EC50 (μM) | Cytotoxicity CC50 (μM) | |
|---|---|---|---|
| A/Udorn/72 (H3N2) M2-WT | A/WSN/33 (M2-N31S + V27A) (H1N1) M2-V27A | ||
|
0.3 ± 0.1 | 1.8 ± 0.2 | 27.6 ± 0.5 |
|
6.4 ± 0.4 | > 30 | 150.5 ± 3.2 |
|
0.07 ± 0.01 | 1.0 ± 0.1 | 74.8 ± 1.2 |
