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. 2016 Dec 4;6(4):187–193. doi: 10.15171/bi.2016.25

Table 3. Genotype and allele frequencies of CTLA4 (+49 A>G and chr2:203868145 A>C) in patients with T1D and controls .

Genes SNP types Patients (%) Controls (%) Odd ratio (95% CI) P value
CTLA4 +49 A>G
AA 36 (72) 41 (82) 1.00 0.24
AG 2 (4) 7 (14) 1.00 0.08
GG 12 (24) 2 (4) 2.17 (0.67-6.96) 0.004*
A 74 (74) 89 (89) 1.2 (0.19-8.72) 0.006*
G 26 (26) 11 (11) 1.03 (0.26-1.93) 0.006*
chr2:203868145
AA 39 (78) 47 (94) 1.00 0.02*
AC 8 (16) 3 (6) 1.00 0.11
CC 3 (6) 0 (0) 0.00 0.08*
A 86 (86) 97 (97) 2.03 (0.61-6.46) 0.005*
C 14 (14) 3 (3) 1.22 (0.06-8.47) 0.005*

Chr2: chromosome 2, SNP: single nucleotide polymorphism.