Table 5. CTLA4 and IL2RA association with glycemic level .
Genes | SNP | Genotype | n | Case | n | Control | P value | ||
Response mean | Difference (95% CI) | Response mean | Difference (95% CI) | ||||||
CTLA4 | +49A/G | AA | 36 | 123.36 | 0.00 | 41 | 94 | -29.36 | 0.0067* |
AG | 2 | 126.5 | 3.14 | 7 | 96.71 | -26.65 | |||
GG | 12 | 133.83 | 10.47 | 2 | 92.5 | -30.86 | |||
chr2:203868145 | AA | 39 | 125.95 | 0.00 | 47 | 94.4 | -31.54 | 0.96 | |
AC | 8 | 124.75 | -1.20 | 3 | 93 | -32.95 | |||
CC | 3 | 130 | 4.05 | 0 | - | - | |||
IL2RA | ss52580101 | CC | 48 | 125.79 | 0.00 | 46 | 94.46 | -31.34 | 0.17 |
CA | 2 | 131 | 5.21 | 4 | 92.75 | -33.04 | |||
AA | 0 | - | - | 0 | - | - | |||
chr10: 6072892 | AA | 42 | 125.33 | 0.00 | 46 | 94.41 | -30.92 | 0.22 | |
AG | 2 | 124.5 | -0.83 | 1 | 94 | -31.33 | |||
GG | 6 | 131.17 | 5.83 | 3 | 93 | -32.33 |
Chr2: chromosome 2, Chr10: chromosome 10, SNP: single nucleotide polymorphism.
* The difference is statistically significant.