Table 6. CTLA4 and IL2RA association with response BMI .
Genes | SNP | Genotype | n | Case | n | Control | P value | ||
Response mean | Difference (95% CI) | Response mean | Difference (95% CI) | ||||||
CTLA4 | +49A/G | AA | 36 | 19.89 | 0.00 | 41 | 20.24 | 0.35 | 0.78 |
AG | 2 | 18.84 | -1.05 | 7 | 19.85 | -0.04 | |||
GG | 12 | 19.54 | -0.34 | 2 | 20.04 | 0.15 | |||
chr2:203868145 | AA | 39 | 19.79 | 0.00 | 47 | 20.1 | 0.31 | 0.24 | |
AC | 8 | 20.06 | 0.27 | 3 | 21.3 | 1.51 | |||
CC | 3 | 18.64 | -1.15 | 0 | - | - | |||
IL2RA | ss52580101 | CC | 48 | 19.78 | 0.00 | 46 | 20.16 | 0.38 | 0.48 |
CA | 2 | 19.23 | -0.56 | 4 | 20.32 | 0.54 | |||
AA | 0 | - | - | 0 | - | - | |||
chr10: 6072892 | AA | 42 | 19.8 | 0.00 | 46 | 20.21 | 0.41 | 0.49 | |
AG | 2 | 20.76 | 0.96 | 1 | 19.59 | -0.21 | |||
GG | 6 | 19.19 | -0.61 | 3 | 19.87 | 0.08 |
Chr2: chromosome 2, Chr10: chromosome 10, SNP: single nucleotide polymorphism.
* The difference is statistically significant.