Table 7. CTLA4 and IL2RA haplotypes association with T1D .
CTLA4 haplotype | ||||
+49A>G | chr2:203868145 | Frequency | Difference (95% CI) | P value |
A | A | 0.745 | 0.00 | - |
G | A | 0.17 | 3.82 (2.34 -5.3) | <0.0001* |
A | C | 0.07 | 0.35 (-2.19 -2.89) | 0.79 |
G | C | 0.015 | 6.78 (2.35 -11.21) | 0.0034* |
IL2RA haplotype | ||||
ss52580101 | chr10: 6072892 | Frequency | Difference (95% CI) | P value |
C | A | 0.865 | 0.00 | - |
C | G | 0.105 | 1.52 (-0.39 -3.43) | 0.12 |
A | A | 0.03 | 0.97 (-3.74 -5.68) | 0.69 |
Chr2: chromosome 2, Chr10: chromosome 10.
* These haplotypes are associated with T1D.