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. Author manuscript; available in PMC: 2018 Jan 1.
Published in final edited form as: Connect Tissue Res. 2016 Jun 16;58(1):15–26. doi: 10.1080/03008207.2016.1200566

Figure 4. The increased ELF3 mRNA levels in OA chondrocytes correlate with hypermethylation of the proximal promoter.

Figure 4

(A) Schematic representation of the proximal human ELF3 promoter sequence (−811bp to −123bp), indicating CpG site positions and percentage of methylation in non-OA and OA human primary chondrocytes, assessed by bisulfite sequencing and (B) ELF3 mRNA levels, assessed by RTqPCR in total RNA isolated from the same cell populations. ***indicates p<0.001.