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. 2015 Oct 1;13(2):277–289. doi: 10.1016/j.celrep.2015.09.032

Figure 6.

Figure 6

ADAR Involvement in Cell Proliferation and Apoptosis

(A) Western blot analysis of ADAR silencing after shRNA lentiviral transduction in MDA-MB-231, MCF7, and BT474 breast cancer cell lines.

(B) ADAR silencing statistically decreases cell proliferation. Cell growth curves for ADAR-knockdown cells (shRNA ADAR) and control cells (shRNA control) in MDA-MB-231, MCF7, and BT474 BC cell lines.

(C) ADAR silencing statistically increases cell apoptosis. Illustration of the percentage of apoptotic cells in ADAR-knockdown cells (shRNA ADAR) and control cells (shRNA control) in MDA-MB-231, MCF7, and BT474 BC cell lines. Error bars depict SDs of three independent experiments.