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. 2017 Feb 27;7:43296. doi: 10.1038/srep43296

Figure 2. Structure of human FNDC5 variants promoter.

Figure 2

(A and B) The human FNDC5 variants have different promoter regions. The CpG island in the FNDC5 gene promoter was predicted by “Methprimer” (http://www.urogene.org/cgi-bin/methprimer/Methprimer.cgi). The CpG island is located at −52 to −442 bp in the FNDC5 promoter, and this region has 61 CpG sites. The CpG island is close to the variant 2 and 3 transcription start sites. Red = CpG island, blue = translational region, black = untranslational region, ChIP primer = chromatin immunoprecipitation primer, MS primer = methylation-specific PCR primer set, TF primer = transcription factor-binding region-specific primer set.