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. 2017 Feb 27;7:43409. doi: 10.1038/srep43409

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Copyright © 2017, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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The kidneys from patients of IgAN and DN were collected for hematoxylin and eosin staining to examine histology, Masson staining for fibrosis analysis and immunohistochemistry staining for p53, ECM related gene expression, p-STAT3 and SOCS7 (A). Quantification of the tubulointerstitial fibrosis (B) in the kidney cortex. Quantify immunohistochemistry staining (C–G). Real time PCR analysis of miR-199a-3p (H). Data were expressed as means ± sd (n = 6); ^#P < 0.05 versus MCD group. Original magnification, x200 or 400.