Table II.
mRNA of genes and serum cytokines
| CT-Sham | RA | RAEX | RAOV | RAOVEX | p | |
|---|---|---|---|---|---|---|
| Median 25-75 P | Median 25-75 P | Median 25-75 P | Median 25-75 P | Median 25-75 P | ||
| Atrogin-1 (Fold change) | 0.999a (0.979-1.011) | 3.355b (3.070-11.590) | 3.230b (1.650-6.620) | 10.320c (8.278-20.257) | 5.125b (3.660-8.080) | 0.001 |
| Myostatin (Fold change) | 1.004a (0.987-1.012) | 0.715a,b (0.490-1.160) | 0.840a (0.508-1.030) | 1.460a (1.000-2.895) | 0.405b (0.210-0.680) | 0.022 |
| MuRF-1 (Fold change) | 0.995a,c (0.989-1.010) | 1.040a,c (0.720-1.530) | 3.810a,b (0.992-5.170) | 5.780b (2.715-8.348) | 0.340c (0.310-1.660) | 0.028 |
| TNF-α (pg/ml) | 54.5a (45.7-93.1) | 56.5a (44.5-66.6) | 59.0a (55.6-76.9) | 54.6a (48.3-72.7) | 40.5a (40.0-58.3) | 0.437 |
| IL-6 (pg/ml) | 103.5a (85.7-125.1) | 90.2a (78.5-119.4) | 91.9a (89.4-103.4) | 93.1a (85.9-143.1) | 120.5a (96.6-133.3) | 0.662 |
CT-Sham group – control group (n = 6); RA group – rheumatoid arthritis group (n = 6); RAEX group – rheumatoid arthritis, who held an acute session of resistance exercise (n = 6); RAOV group – ovariectomy with rheumatoid arthritis (n = 6); RAOVEX group – ovariectomy with rheumatoid arthritis who held an acute session of resistance exercise (n = 6). Data are expressed as median and 25-75th percentiles. ANOVA – Kruskal-Wallis test. Different letters = P < 0.05 (e.g. a is difference of b and c; a,c is difference of b; a,c is not difference of c)