. 2014 Apr 29;3(2):93–98. doi: 10.1530/EC-14-0021
This work is licensed under a Table 3.
Characteristics of the different groups of patients with acromegaly according to disturbances of glucose metabolism.
| Parameters | NGT | ECMDs | DM | P value |
|---|---|---|---|---|
| Number of patients | 21 | 25 | 51 | – |
| Male/female, n | 7/14 | 4/21 | 5/46 | 0.050 |
| Age (years) | 47±12 | 53±12 | 60±11 | <0.001 |
| BMI (kg/m2) | 28.4±2.8 | 31.2±5.4 | 33.1±5.8 | 0.009 |
| SBP (mmHg) | 131±21 | 132±16 | 144±21 | 0.014 |
| DBP (mmHg) | 83±12 | 82±11 | 89±13 | 0.061 |
| Estimated duration of acromegaly (years) | 9.0 (5.4–12.8) | 11.0 (6.8–20.0) | 15.0 (8.0–24.0) | 0.013 |
| Basal GH (mU/l) | 4.2 (1.1–8.4) | 6.2 (3.1–16.4) | 5.7 (2.2–15.6) | 0.609 |
| IGF1 (ng/ml) | 223 (147–436) | 403 (252–663) | 310 (194–582) | 0.460 |
| IGF1 Z-score | 2.1 (0.7–4.4) | 5.1 (3.3–6.6) | 4.5 (2.3–6.5) | 0.002 |
| Previous TSS, n (%) | 14 (67) | 10 (40) | 14 (27) | 0.008 |
| Use of SSA, n (%) | 11 (54) | 19 (76) | 35 (69) | 0.222 |
| Acromegaly controlled, n (%) | 8 (38) | 3 (12) | 11 (22) | 0.105 |
Data are given as absolute numbers (n) and percentage (%), mean±s.d. or median (interquartile range). SBP, systolic blood pressure; DBP, diastolic blood pressure; GH, growth hormone; TSS, transsphenoidal surgery; SSA, somatostatin analogue; NGT, normal glucose tolerance; ECMDs, early carbohydrate metabolism disorders; DM, diabetes mellitus.