Table 4.
Comparison of NAFLD US grades, NFS and BARD score within and between groups
Variable | Control (32)
|
P-value | Orlistat (45)
|
P-value | P-value between groups | ||
---|---|---|---|---|---|---|---|
0 week | 16 weeks | 0 week | 16 weeks | ||||
US grades | 1.78±0.71 | 1.49±0.80 | 0.062 | 2.02±0.73 | 1.20±0.94 | <0.001** | 0.016$ |
0 | 0 | 2 (6.25) | 0 | 11 (24.44) | |||
1 | 12 (37.5) | 17 (53.12) | 11 (24.44) | 19 (42.22) | |||
2 | 15 (46.87) | 9 (28.12) | 22 (48.89) | 10 (22.22) | |||
3 | 6 (15.62) | 4 (12.5) | 12 (26.67) | 5 (11.11) | |||
NFS score | 1.25±0.44 | 1.28±0.46 | 0.705 | 1.22±0.42 | 1.20±0.40 | 0.655 | 0.426 |
Low | 24 (75) | 23 (71.875) | 35 (77.78) | 36 (80) | |||
Intermediate | 8 (25) | 9 (28.125) | 10 (22.22) | 9 (20) | |||
High | 0 | 0 | 0 | 0 | |||
BARD score | 0.91±0.99 | 1.03±1.06 | 0.157 | 1.20±0.84 | 1.09±0.87 | 0.248 | 0.137 |
Low | 26 (81.25) | 25 (78.12) | 38 (84.44) | 39 (86.67) | |||
High | 6 (18.75) | 7 (21.875) | 7 (22.22) | 8 (17.78) |
Notes: Data are expressed as n (%).
P-value is <0.001 within groups,
P-value is <0.05 between groups.
Abbreviations: ALT, alanine aminotransferase; AST, aspartate aminotransferase; BARD, body mass index plus AST/ALT ratio plus presence of diabetes; NAFLD, nonalcoholic fatty liver disease; NFS, NAFLD fibrosis score; US, ultrasound.