Figure 2.

Biomarker-based individualization of immunosuppression of kidney transplant recipients will require use of multiple testing strategies. The x axis depicts the time points relative to the transplantation (Tx) when these biomarkers could be applied. The dashed horizontal line separates the conventional clinical and laboratory tests that are used currently. The continuous horizontal line describes common clinical immunologic events encountered in Tx with respect to times after Tx; the widths of the T cell–mediated rejection (TCMR) and ABMR lines refer to frequencies of these events. PRA, panel of reactive antibody.