Author	Study design	Clear definition of the study population	Clear description of assessment of the main outcome	Clear description of assessment of all outcomes	Description of missing data
Fedeli U et al.19	Retrospective	Yes	Yes	Yes	NA
Campagna M et al.17	Retrospective	Yes	Yes	Yes	NA
Cologni L et al.18	Retrospective	Yes	Yes	Yes	NA
Fortunato F et al.13	Retrospective	Yes	Yes	Yes	NA
Porru S et al.20	Retrospective	Yes	Yes	Yes	NA
Stroffolini T et al.14	Retrospective	Yes	Yes	Yes	No
Esposito S et al.21	Retrospective	Yes	Yes	Yes	NA
Alicino C et al.22	Prospective	Yes	Yes	Yes	Yes
Copello F et al.15	Prospective	Yes	Yes	Yes	No
Campagna M et al.16	Prospective	Yes	Yes	Yes	Yes