Figure 1.

Aldh1a1/Gpx1 knockout (KO) mice show significantly reduced mean latency to fall from the rotarod compared to age-matched wild-type (WT) mice. Data are expressed as the mean ± SEM of the number of mice in parentheses. Data were analyzed using a general linear model. The Tukey–Kramer method was used for adjustment for multiple comparisons. *p < 0.05, WT vs KO at the indicated time-points.